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The Oxford Textbook of Clinical Research Ethics

The Oxford Textbook of Clinical Research Ethics PDF Author: Ezekiel J. Emanuel
Publisher: OUP USA
ISBN: 0199768633
Category : Medical
Languages : en
Pages : 848

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Book Description
The Oxford Textbook of Clinical Research Ethics is the first comprehensive and systematic reference on clinical research ethics. Under the editorship of experts from the U.S. National Institutes of Health of the United States, the book's 73 chapters offer a wide-ranging and systematic examination of all aspects of research with human beings. Considering the historical triumphs of research as well as its tragedies, the textbook provides a framework for analyzing the ethical aspects of research studies with human beings. Through both conceptual analysis and systematic reviews of empirical data, the contributors examine issues ranging from scientific validity, fair subject selection, risk benefit ratio, independent review, and informed consent to focused consideration of international research ethics, conflicts of interests, and other aspects of responsible conduct of research. The editors of The Oxford Textbook of Clinical Research Ethics offer a work that critically assesses and advances scholarship in the field of human subjects research. Comprehensive in scope and depth, this book will be a crucial resource for researchers in the medical sciences, as well as teachers and students.

The Oxford Textbook of Clinical Research Ethics

The Oxford Textbook of Clinical Research Ethics PDF Author: Ezekiel J. Emanuel
Publisher: OUP USA
ISBN: 0199768633
Category : Medical
Languages : en
Pages : 848

View

Book Description
The Oxford Textbook of Clinical Research Ethics is the first comprehensive and systematic reference on clinical research ethics. Under the editorship of experts from the U.S. National Institutes of Health of the United States, the book's 73 chapters offer a wide-ranging and systematic examination of all aspects of research with human beings. Considering the historical triumphs of research as well as its tragedies, the textbook provides a framework for analyzing the ethical aspects of research studies with human beings. Through both conceptual analysis and systematic reviews of empirical data, the contributors examine issues ranging from scientific validity, fair subject selection, risk benefit ratio, independent review, and informed consent to focused consideration of international research ethics, conflicts of interests, and other aspects of responsible conduct of research. The editors of The Oxford Textbook of Clinical Research Ethics offer a work that critically assesses and advances scholarship in the field of human subjects research. Comprehensive in scope and depth, this book will be a crucial resource for researchers in the medical sciences, as well as teachers and students.

Ethical Issues in Clinical Research

Ethical Issues in Clinical Research PDF Author: Bernard Lo
Publisher: Lippincott Williams & Wilkins
ISBN: 1451152779
Category : Medical
Languages : en
Pages : 300

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Book Description
This book teaches researchers how to resolve the ethical dilemmas that can arise at any stage in clinical research. In addition to explaining pertinent regulations and laws, Dr. Lo helps investigators understand the gaps and uncertainties in regulations, as well as situations in which merely complying with the law may not fulfill ethical responsibilities. Most chapters include real-life examples that the author walks through, discussing the salient issues and how to approach them. This book can be used in courses on research ethics that are required or encouraged by major National Institutes of Health grants in academic health centers.

Success in Academic Surgery: Clinical Trials

Success in Academic Surgery: Clinical Trials PDF Author: Timothy M. Pawlik
Publisher: Springer Science & Business Media
ISBN: 1447146794
Category : Medical
Languages : en
Pages : 183

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Book Description
Surgical education is a rapidly expanding area of surgical research and career interest, and as the Association for Academic Surgery (AAS) Fall Courses (www.aasurg.org) and International courses offer more and more specialty tracking there is a greater need for an accompanying textbook to supplement the material presented in the courses.

Empfehlungen zur Begutachtung klinischer Studien durch Ethik-Kommissionen

Empfehlungen zur Begutachtung klinischer Studien durch Ethik-Kommissionen PDF Author: Hans-Heinrich Raspe
Publisher: Deutscher Ärzteverlag
ISBN: 3769113055
Category : Ethics committees
Languages : de
Pages : 282

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Book Description


Rethinking the Ethics of Clinical Research

Rethinking the Ethics of Clinical Research PDF Author: Alan Wertheimer
Publisher: Oxford University Press
ISBN: 0199743517
Category : Medical
Languages : en
Pages : 369

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Book Description
Introduction -- Facing up to paternalism in research ethics -- Preface to a theory of consent transactions in research : beyond valid consent -- Should we worry about money? -- Exploitation in clinical research -- The interaction principle.

Stakeholders and Ethics in Healthcare

Stakeholders and Ethics in Healthcare PDF Author: Lisa A. Martinelli
Publisher: Routledge
ISBN: 1000545903
Category : Medical
Languages : en
Pages : 216

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Book Description
This ground-breaking book uses organizational ethics and stakeholder theory to explore the ethical accountability of leadership in healthcare organizations to their distinct vulnerable stakeholder communities. The book begins with a discussion of the moral agency of healthcare organizations and introduces stakeholder theory. It then looks at key ethical challenges in relation to the confidentiality and privacy of health care data, before turning to child health and interventions around issues such as obesity, maltreatment, and parenting. The book ends by focusing on ethics of care in relation to older people and people with disabilities. An insightful contribution to thinking about ethics for contemporary healthcare management and leadership, this interdisciplinary book is of interest to readers with a background in healthcare, business and management, law, bioethics, and theology.

BRAF Targets in Melanoma

BRAF Targets in Melanoma PDF Author: Ryan J. Sullivan
Publisher: Springer
ISBN: 1493921436
Category : Medical
Languages : en
Pages : 204

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Book Description
​This volume contains a collection of writings from the leaders in the fields of Molecular Biology and Melanoma Research which will begin to tell the ever-expanding story of the most recent findings, discoveries, and potential of BRAF-directed targets in melanoma. Recent research has shown that BRAF inhibitors are effective for a short period of time, but there is little hope that this drugs as single agents will lead to durable benefit in a majority of patients. Among scientists and researchers who work in drug discovery, there is a lot of interest in the development of molecularly targeted cancer agents. Namely, the identification of a molecular target, the selection of molecules which effectively inhibit this target. What is starkly different about the development of this class of compounds, however, is that the mechanism of action of these agents are not as straightforward as was once previously assumed and the mechanisms of resistance that tumor cells employ to evade complete destruction are unlike any that have been described before. These discoveries in addition to utilization of modern molecular biology techniques have led to a series of hypotheses regarding which other types of molecules could be used in combination with BRAF-inhibitors in hopes of revolutionizing the potential of therapeutics in melanoma.

An Ethical Framework for Global Governance for Health Research

An Ethical Framework for Global Governance for Health Research PDF Author: Kiarash Aramesh
Publisher: Springer Nature
ISBN: 3030311325
Category : Philosophy
Languages : en
Pages : 180

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Book Description
This book provides a comprehensive description and ethical analysis of one of the most challenging areas: international health research. Furthermore, it provides a vivid portrait of the current situation of global governance for health research and its main challenges and suggests a comprehensive and universal ethical framework based on the existing theories and frameworks. This work is a must-read for all the students, scholars, professionals, activists, and policy-makers who are involved or interested in the global health research enterprise and its governance and ethics.

Clinical Ethics for Consultation Practice

Clinical Ethics for Consultation Practice PDF Author: Joseph T. Bertino
Publisher: Springer Nature
ISBN: 3030901823
Category : Medical
Languages : en
Pages : 162

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Book Description
This book provides a robust analysis of the history of clinical ethics, the philosophical theories that support its practice, and the practical institutional criteria needed to become a practicing clinical ethicist. Featuring cases and a step-by-step approach, this book combines knowledge points associated with moral philosophy and medicine with general skill objectives for ethics consultants. The book aids in developing analytic moral reasoning skills for clinical ethicists, fostering the comprehensive education and professional development of clinical ethics consultants. In addition, it offers key components of how an ethics consultation curriculum manifest in an educational venue for clinical ethicists are illustrated. Adaptable and relevant for educating multiple disciplines in health care, this resource enables ethicists to understand the philosophical foundations and practical application of clinical ethics.

Ethics and Governance of Biomedical Research

Ethics and Governance of Biomedical Research PDF Author: Daniel Strech
Publisher: Springer
ISBN: 3319287311
Category : Philosophy
Languages : en
Pages : 225

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Book Description
In this book, scholars with different disciplinary and national backgrounds argue for possible answers and analyse case studies on current issues of governance in biomedical research. These issues comprise among others the research-care distinction, risk evaluation in early human trials, handling of incidental findings, nocebo effects, cluster randomized trials, publication bias, or consent in biobank research. This book demonstrates how new technologies and research possibilities multiply or intensify already known governance challenges, leaving room for ethical analysis and complex moral choices. Clinical researchers, research ethics committee members and research ethicists have all to deal with such challenges on a daily basis. While general reflection on core concepts of research ethics is seldom pointless, those confronted with hard moral choices do need more practical and contextualized reflection on the said issues. This book particularly provides such contextualized reflections and aims to inform all those who study, conduct, regulate, fund, or participate in biomedical research.