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Human Cytogenetic Cancer Markers

Human Cytogenetic Cancer Markers PDF Author: Sandra R. Wolman
Publisher: Humana Press
ISBN: 9781461284376
Category : Medical
Languages : en
Pages : 485

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Book Description
Seventeen cutting-edge chapters review both basic research and clinical applications of chromosomal markers of cancer. The new markers offer great promise, not only for their clinical utility in diagnosis, prognosis, and disease monitoring, but also for their contributions to a better understanding of the mechanisms of tumor development and progression. The chapters-all written by leading authorities-skillfully reveal fresh insights into the translational role of cytogenetics in identifying the cellular and molecular changes that occur in cancer. Coverage is devoted to many tissue systems-colon, breast, prostate, lung, skin, brain, and kidney-where the diagnostic and prognostic utility of chromosome markers is clearly demonstrated. A seminal book certain to become the front-line reference and authoritative resource needed by all scientists and clinicians engaged in cancer research, diagnosis, and management.

Human Cytogenetic Cancer Markers

Human Cytogenetic Cancer Markers PDF Author: Sandra R. Wolman
Publisher: Humana Press
ISBN: 9781461284376
Category : Medical
Languages : en
Pages : 485

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Book Description
Seventeen cutting-edge chapters review both basic research and clinical applications of chromosomal markers of cancer. The new markers offer great promise, not only for their clinical utility in diagnosis, prognosis, and disease monitoring, but also for their contributions to a better understanding of the mechanisms of tumor development and progression. The chapters-all written by leading authorities-skillfully reveal fresh insights into the translational role of cytogenetics in identifying the cellular and molecular changes that occur in cancer. Coverage is devoted to many tissue systems-colon, breast, prostate, lung, skin, brain, and kidney-where the diagnostic and prognostic utility of chromosome markers is clearly demonstrated. A seminal book certain to become the front-line reference and authoritative resource needed by all scientists and clinicians engaged in cancer research, diagnosis, and management.

Human Cytogenetic Cancer Markers

Human Cytogenetic Cancer Markers PDF Author: Sandra R. Wolman
Publisher: Springer Science & Business Media
ISBN: 1461239524
Category : Medical
Languages : en
Pages : 485

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Book Description
Seventeen cutting-edge chapters review both basic research and clinical applications of chromosomal markers of cancer. The new markers offer great promise, not only for their clinical utility in diagnosis, prognosis, and disease monitoring, but also for their contributions to a better understanding of the mechanisms of tumor development and progression. The chapters-all written by leading authorities-skillfully reveal fresh insights into the translational role of cytogenetics in identifying the cellular and molecular changes that occur in cancer. Coverage is devoted to many tissue systems-colon, breast, prostate, lung, skin, brain, and kidney-where the diagnostic and prognostic utility of chromosome markers is clearly demonstrated. A seminal book certain to become the front-line reference and authoritative resource needed by all scientists and clinicians engaged in cancer research, diagnosis, and management.

Molecular Pathology of Early Cancer

Molecular Pathology of Early Cancer PDF Author: Sudhir Srivastava
Publisher: IOS Press
ISBN: 9789051993738
Category : Medical
Languages : en
Pages : 512

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Book Description
This book describes the principles and the application of the existing molecular methodology for the detection of early cancer. Discussion focuses on the molecular changes characterizing preneoplastic lesions; molecular targets for early detection; validation of molecular targets; and new diagnostic technology for early detection. The advantages of molecular detection over current methods are examined, as well as the importance of identifying and characterizing preneoplastic lesions. In addition to the uses of highly specific molecular probes to detect early cancer, this book demonstrates the many ways in which molecular markers serve oncology. While meeting pressing needs in the practice of medicine, molecular detection of early cancer scientifically necessitates a confrontation with the biology of cancer, such as the genetic determinants of progression, regression, dormancy, and invasion. This work not only discusses the diagnostic value of these molecular methods but views their practical benefits against a background of conventional morphology.

Medical Cytogenetics

Medical Cytogenetics PDF Author: Mark Hon Fong L.
Publisher: CRC Press
ISBN: 1482292998
Category : Medical
Languages : en
Pages : 728

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Book Description
The only monograph on cytogenetics for the pathologist, this up-to-the-minute reference/text contains the most up-to-date research findings on many important topics in medical genetics-notably FISH (fluorescent in situ hybridation)-based molecular cytogenetic technologies and spectral karyotyping. An excellent resource for cytogeneticists prepar

Management of Prostate Cancer

Management of Prostate Cancer PDF Author: Eric A. Klein
Publisher: Springer Science & Business Media
ISBN: 1592597149
Category : Medical
Languages : en
Pages : 372

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Book Description
Prostate cancer remains the most common malignant tumor in elderly men. The National Cancer Institute estimated 210,000 new cases of prostate cancer in 1997. There is, however, no means of documenting the true incidence of prostate cancer because of the difficulty in detecting all cases. Even using yearly rectal exams, PSA determinations, and ultrasound-guided prostate biopsies, many cases are missed. Suffice it to say that prostate cancer is a widely occurring disease in men and early detection and treatment are extremely important. When I trained in Urology under Dr. Reed Nesbit at the University of Michigan from 1956 to 1959, the diagnosis of prostate cancer was made by a rectal examination and an acid phosphatase determination. If there was a small nodule in the prostate, then an anterior-posterior X-ray of the pelvis was obtained to look for possible bony metastases. If the acid phosphatase was normal and there was no evidence ofa bony metastasis, the prostate was exposed through the perineal approach and a biopsy of the nodule was obtained and sent for frozen section to Pathology to determine if it was indeed a cancer of the prostate. If the biopsy came back positive, the surgeon then proceeded to do a radical perineal prostatectomy. In those days, we usually did eight to ten radical perineal prostatectomies yearly. Many times the nodule that was biopsied was benign, and the incision was simply closed.

Clinical Research in Diabetes and Obesity, Volume 2

Clinical Research in Diabetes and Obesity, Volume 2 PDF Author: Boris Draznin
Publisher: Springer Science & Business Media
ISBN: 1475739060
Category : Medical
Languages : en
Pages : 392

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Book Description
An unprecedented compilation of state-of-the-art advances in clinical research by premier clinical scientists around the world. This volume discusses the methods of clinical research and the interpretation of their results in studies of normal individuals, obese subjects, and patients with diabetes mellitus. Along the way, the authoritative contributors writing here illuminate how changes in the hormone action and substrate metabolism of healthy humans may lead to obesity and noninsulin-dependent diabetes mellitus.

ISCN 2005

ISCN 2005 PDF Author: Lisa G. Shaffer
Publisher: Karger Medical and Scientific Publishers
ISBN: 3805580193
Category : Medical
Languages : en
Pages : 137

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Book Description
This publication combines and extends the now classic system of human cytogenetic nomenclature prepared by expert committees and published in collaboration with Cytogenetic and Genome Research (formerly: Cytogenetics and Cell Genetics ) since 1963. Revised and finalized by the ISCN Committee and its advisors at a meeting in Vancouver, BC, in December 2004, it updates, corrects and incorporates all previous human cytogenetic nomenclature recommendations into one systematically organized publication. It thus supersedes the previous compilations in ISCN 1985 and its supplement, ISCN 1991 , the Guidelines for Cancer Cytogenetics , and ISCN 1995 . What s new in ISCN 2005? the G- and R-banded karyotypes have been replaced by new ones reflecting higher band-level resolutions new ideograms at the 300-band and 700-band level have been added the in situ hybridization nomenclature has been modernized, simplified, and expanded new examples reflecting unique situations are included a basic nomenclature for recording array comparative genomic hybridization results is introduced ISCN 2005 also contains a detachable fold-out of the normal human karyotype, consisting of photographs of G-banded and R-banded chromosomes at the commonly examined 550-band resolution stage and their diagrammatic representations a useful aid for human cytogeneticists, technicians, and students.

Women and Health

Women and Health PDF Author: Marlene B. Goldman
Publisher: Elsevier
ISBN: 0080543855
Category : Medical
Languages : en
Pages : 1282

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Book Description
Women and Health is a comprehensive reference which addresses health issues affecting women of all ages--adolescence through maturity. It goes far beyond other books on this topic which concentrate only on reproductive health, and has a truly international perspective. It covers key issues ranging from osteoporosis to breast cancer and other cancers, domestic violence, sexually transmitted diseases, occupational hazards, eating disorders, heart disease and other chronic illnesses, substance abuse, and societal and behavioral influences on health. Women and Health covers not only those conditions that are unique to or occur more frequently in women, but also those that present differently or are treated differently in women. Key Features: * Comprehensive, in-depth review of all aspects of women's health * Highlights key women's health issues including osteoporosis, domestic violence, breast cancer, menopause, infertility, heart disease, and many others * Addresses international women's health issues from a human rights and cultural perspective * Presents the latest research and clinical findings from leaders in their respective fields * Highlights controversies in treatment modalities * Challenges the medical community to address the impact of gender on health * Expands our thinking about the perceptions of disease and disorders in women * Challenges current status quo in health care delivery

The Genetic Basis of Common Diseases

The Genetic Basis of Common Diseases PDF Author: Richard A. King
Publisher: Oxford University Press
ISBN: 0195125827
Category : Medical
Languages : en
Pages : 1091

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Book Description
Discusses the role of genes in complex diseases. Also includes chapters on genetic counseling, evolution and disease, genetic effects of therapy, pharmacogenetics, and the role of mitochondrial variation.

ISCN 1995

ISCN 1995 PDF Author: Standing Committee on Human Cytogenetic Nomenclature
Publisher: Karger Medical and Scientific Publishers
ISBN: 9783805562263
Category : Technology & Engineering
Languages : en
Pages : 126

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Book Description
This publication combines and extends the now classic system of human cytogenetic nomenclature that has been prepared by expert committees and published in, or in collaboration with, Cytogenetics and Cell Genetics since 1963. The current ISCN committee and its advisors finalized the report at a meeting in Memphis, Tennessee in October 1994. It updates, corrects and combines all previous human cytogenetic nomenclature recommendations into one systematically organized publication. ISCN 1995 includes, supersedes, and reorganizes the previous compilation in ISCN 1985 and its supplement, ISCN 1991, the Guidelines for Cancer Cytogenetics. Also, some minor inconsistencies of the previous compilations are corrected and clarified.